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小鼠 Raf-1/RAF1 基因全長cDNA ORF克隆 (表達載體)

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    小鼠 RAF1 cDNA Clone產品資訊
    註冊碼:NM_029780.3
    cDNA基因長度:1947bp
    cDNA基因描述:Full length Clone DNA of Mus musculus v-raf-leukemia viral oncogene 1.
    基因別名:Apn, Cd13, Lap-1, Lap1, p150
    分子種屬:Mouse
    載體:pCMV3-untagged
    Plasmid:
    限制性酶切位點:
    Tag序列:
    序列資訊:
    Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with RAF1 qPCR primers for gene expression analysis, MP200311 )
    Promoter:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    Antibiotic in E.coli:Ampicillin
    Antibiotic in mammalian cell:Hygromycin
    運輸條件:Each tube contains lyophilized plasmid.
    儲存方法:The lyophilized plasmid can be stored at room temperature for three months.
    Product nameProduct name
    研究背景

    RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Size / Price
    貨號: MG50287-UT
    目錄價: 
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    Datasheet & Documentation

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