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小鼠 NCF2 / NCF-2 / P67phox 基因全長cDNA ORF克隆 (表達載體)

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Mouse NCF2 cDNA Clone產品資訊
註冊碼:NM_010877.4
cDNA基因長度:1578bp
cDNA基因描述:Full length Clone DNA of Mus musculus neutrophil cytosolic factor 2.
基因別名:NOXA2, Ncf-2, p67phox
分子種屬:Mouse
載體:pCMV3-untagged
Plasmid:
限制性酶切位點:
Tag序列:
序列資訊:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Ampicilin
Antibiotic in mammalian cell:Hygromycin
運輸條件:Each tube contains lyophilized plasmid.
儲存方法:The lyophilized plasmid can be stored at room temperature for three months.
小鼠 NCF2 / NCF-2 / P67phox 基因全長cDNA ORF克隆 (表達載體) on other vectors
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研究背景

NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

參考資料
  • Wientjes FB. et al., 1996, Semin Cell Biol. 6 (6): 357-65.
  • DeLeo FR. et al., 1997, J Leukoc Biol. 60 (6): 677-91.
  • Dorseuil O. et al., 1997, C R Seances Soc Biol Fil. 191 (2): 237-46.
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    貨號: MG52449-UT
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