|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-GFPSpark 標籤||MG50492-ACG|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-OFPSpark 標籤||MG50492-ACR|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-Flag 標籤||MG50492-CF|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-His 標籤||MG50492-CH|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-Myc 標籤||MG50492-CM|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), C-HA 標籤||MG50492-CY|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF(克隆載體)||MG50492-M|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), N-Flag 標籤||MG50492-NF|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), N-His 標籤||MG50492-NH|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), N-Myc 標籤||MG50492-NM|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體), N-HA 標籤||MG50492-NY|
|小鼠 MMP-7/MMP7 基因全長cDNA ORF克隆 (表達載體)||MG50492-UT|
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological and pathological processes such as morphogenesis, differentiation, angiogenesis, tissue remodeling, and tumor invasion. MMPs are synthesized as pro-enzymes and converted to active form by extracellular proteinases. MMP7, also referred to as matrilysin, is the smallest member of the MMP family and differs from other MMP members in that it lacks the C-terminal hemopexin-like domain. MMP7 is produced primarily by mucosal epithelia, and is capable of degrading various ECM proteins including proteoglycans, fibronectin, elastin and casein. This enzyme serves essential functions in both innate defense and wound healing, and appears to be one of the most important MMPs in human colon cancers. It has been reported that MMP7 contributes to tumor malignancy probably by cleaving cell surface proteins such as Fas ligand, degradation of IgG or inducing E-cadherin-mediated cell aggregation. In addition, matrilysin is also identified as a mediator of pulmonary fibrosis and a potential therapeutic target.