LYVE1 cDNA ORF Clone, Human, C-DDK (Flag®) tag

Cat: HG10237-M-F

This product is not available, please contact order@sinobiological.com for relevant product if required.

Contact us:
215-583-7898
order@sinobiological.com
Distributors
All LYVE1 Reagents
CRO Services

All LYVE1 Reagents
LYVE1 cDNA ORF Clone, Human, C-DDK (Flag®) tag General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
969 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human lymphatic vessel endothelial hyaluronan receptor 1 with Flag tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV2-FLAG
Restriction Sites
KpnI + XhoI (5.4kb + 1.02kb)
Tag Sequence
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
LYVE1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

LYVE1 cDNA ORF Clone, Human, C-DDK (Flag®) tag Alternative Names
CRSBP-1 cDNA ORF Clone, Human;HAR cDNA ORF Clone, Human;LYVE-1 cDNA ORF Clone, Human;XLKD1 cDNA ORF Clone, Human
LYVE1 Background Information

LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental purposes. It also functions as a ligand-specific transporter trafficking between intracellular organelles and the plasma membrane. It plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding. It may act as an hyaluronan transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Full Name
lymphatic vessel endothelial hyaluronan receptor 1
References
  • Jackson DG. (2003) The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1. Trends Cardiovasc Med. 13(1):1-7.
  • Banerji S, et al. (1999) LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol. 144(4):789-801.
  • Mouta Carreira C, et al. (2001) LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res. 61(22): 8079-84.
  • Cursiefen C, et al. (2002) Lymphatic vessels in vascularized human corneas: immunohistochemical investigation using LYVE-1 and podoplanin. Invest Ophthalmol Vis Sci. 43(7):2127-35.
  • LYVE1 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    LYVE1 cDNA ORF Clone in Cloning Vector, Mouse MG50065-M
    LYVE1 cDNA ORF Clone, Mouse, untagged MG50065-UT
    LYVE1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50065-ACGLN
    LYVE1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50065-ACG
    LYVE1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50065-ACR
    LYVE1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50065-CF
    LYVE1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50065-NF
    LYVE1 cDNA ORF Clone, Mouse, C-His tag MG50065-CH
    LYVE1 cDNA ORF Clone, Mouse, N-His tag MG50065-NH
    LYVE1 cDNA ORF Clone, Mouse, C-HA tag MG50065-CY
    LYVE1 cDNA ORF Clone, Mouse, N-HA tag MG50065-NY
    LYVE1 cDNA ORF Clone, Mouse, C-Myc tag MG50065-CM
    LYVE1 cDNA ORF Clone, Mouse, N-Myc tag MG50065-NM
    LYVE1 qPCR Primer Pairs, Mouse MP200065

    LYVE1 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    LYVE1 cDNA ORF Clone in Cloning Vector, Human HG10237-M
    LYVE1 cDNA ORF Clone, Human, untagged HG10237-UT
    LYVE1 cDNA ORF Clone, Human, C-GFPSpark® tag HG10237-ACG
    LYVE1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10237-ACGLN
    LYVE1 cDNA ORF Clone, Human, C-OFPSpark® tag HG10237-ACR
    LYVE1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10237-CF
    LYVE1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10237-NF
    LYVE1 cDNA ORF Clone, Human, C-His tag HG10237-CH
    LYVE1 cDNA ORF Clone, Human, N-His tag HG10237-NH
    LYVE1 cDNA ORF Clone, Human, C-HA tag HG10237-CY
    LYVE1 cDNA ORF Clone, Human, N-HA tag HG10237-NY
    LYVE1 cDNA ORF Clone, Human, C-Myc tag HG10237-CM
    LYVE1 cDNA ORF Clone, Human, N-Myc tag HG10237-NM
    LYVE1 qPCR Primer Pairs, Human HP100287
    info info
    添加购物车成功! 添加购物车失败!