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Insulin / INS  Protein, Antibody, ELISA Kit, cDNA Clone

描述:   
表達宿主: Yeast  
  • Slide 1
11038-HNAY-100
11038-HNAY-50
100 µg 
50 µg 
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Insulin / INS 相關信號通路

Insulin / INS 相關蛋白、抗體、cDNA基因、ELISA試劑盒

Insulin / INS 概述&蛋白信息

Insulin / INS 研究背景

亞單位結構: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
亞細胞定位: Secreted.
相關疾病 : Hyperproinsulinemia, familial (FHPRI) [MIM:176730]: An autosomal dominant condition characterized by elevated levels of serum proinsulin-like material. Note=The disease is caused by mutations affecting the gene represented in this entry.
Diabetes mellitus, insulin-dependent, 2 (IDDM2) [MIM:125852]: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical features are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. Note=The disease is caused by mutations affecting the gene represented in this entry.
Diabetes mellitus, permanent neonatal (PNDM) [MIM:606176]: A rare form of diabetes distinct from childhood- onset autoimmune diabetes mellitus type 1. It is characterized by insulin-requiring hyperglycemia that is diagnosed within the first months of life. Permanent neonatal diabetes requires lifelong therapy. Note=The disease is caused by mutations affecting the gene represented in this entry.
Maturity-onset diabetes of the young 10 (MODY10) [MIM:613370]: A form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似的序列: Belongs to the insulin family.
General information above from UniProt

Insulin / INS 別稱

IDDM1, [Human]

Insulin / INS 相關文獻

請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”