Anti-Insulin Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
A synthetic peptide corresponding to the center region of the Human Insulin / INS
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Insulin / INS, and purified by antigen affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Insulin Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Insulin Antibody (Rabbit Polyclonal antibody) Images
Immunochemical staining of human INS in human pancreas with rabbit polyclonal antibody (1:20000, formalin-fixed paraffin embedded sections).
Anti-Insulin Antibody Alternative Names
Anti-IDDM Antibody;Anti-IDDM1 Antibody;Anti-IDDM2 Antibody;Anti-ILPR Antibody;Anti-INS Antibody;Anti-IRDN Antibody;Anti-MODY10 Antibody
Insulin Background Information
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Veedfald S, Plamboeck A, Deacon C F, et al. Cephalic phase secretion of insulin and other enteropancreatic hormones in humans[J]. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016, 310(1): G43-G51.