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流感 Matrix Protein 1 (M1)

義翹神州研發提供流感相關的科研試劑,包括重組蛋白、抗體、基因、ELISA試劑盒。產品涵蓋流感病毒的主要抗原分子,血凝素蛋白、神經氨酸酶、基質蛋白1、非結構蛋白1、非結構蛋白2、核蛋白。    

流感  Matrix Protein 1 (M1蛋白, 抗體, ELISA試劑盒 and 基因 產品

M1 蛋白M1 抗體M1 ELISA試劑盒M1 基因
ProductMoleculeCat No.Package/Price 
甲型流感 H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix 蛋白 1 / M1 蛋白 (His 標籤)M140010-V07E-10
40010-V07E-100
40010-V07E-50
10 µg/
100 µg/
50 µg/
Add to Cart
Add to Cart
Add to Cart
甲型流感 H7N9 (A/Anhui/1/2013) Matrix 蛋白 1 / M1 蛋白 (His 標籤)M140107-V08E-10
40107-V08E-50
40107-V08E-100
10 µg/
50 µg/
100 µg/
Add to Cart
Add to Cart
Add to Cart
甲型流感 H1N1 (A/Brevig Mission/1/1918) Matrix 蛋白 1 / M1 蛋白 (His 標籤)M140211-V07E-100
40211-V07E-50
100 µg/
50 µg/
Add to Cart
Add to Cart
甲型流感 H3N2 (A/Aichi/2/1968) Matrix 蛋白 1 / M1 蛋白 (His 標籤)M140215-V07E-100
40215-V07E-50
100 µg/
50 µg/
Add to Cart
Add to Cart
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流感 Matrix Protein 1 (M1) 背景

Influenza virus matrix protein 1 (M1) has been shown to plays important roles during replication, assembly and budding of the virus. The M1 protein of influenza virus regulates the bi-directional transport of ribonucleoprotein (RNP) into and out of the nucleus. At the beginning of infection, the incoming RNP is transported into the nucleus only after detachment from M1, where RNP is involved in transcription/replication of the viral genome. In the late stage of infection, M1 inhibits viral RNA polymerase activity by binding to RNP, which may be a signal for RNP-transport from the nucleus to the cell surface. Finally, M1 mediates the association of RNP with viral envelope glycoproteins on the inner surface of the cytoplasmic membrane, which then promotes the virion formation and budding. The matrix protein M1, the organizer of assembly of influenza virus, interacts with other virus components and with cellular membranes. It has been proposed that M1 binding to lipids is mediated by its polybasic region. It been identified heat shock cognate protein 70 (Hsc70) is directly associated with M1 and therefore is required for viral production. The interactions of M1 with viral envelope proteins are essential to direct M1 to the plasma membrane for influenza virus particle release.

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