Anti-ST2 Antibody

Cat: 10105-MM09

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Anti-ST2 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-ST2 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human ST2
No cross-reactivity in ELISA and WB with Human IL1R1 / CD121a Human IL1R2 / IL1RB / CD121b Human IL1F3 / IL1RA Human cell lysate (293 cell line)
Recombinant Human IL1RL1 protein (Catalog#10105-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 extracellular domain (rh IL1RL1; Catalog#10218-HCCH; Met 1-Phe 328; NP_003847.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #1E5F10D3
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ST2 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ST2 Antibody Alternative Names
Anti-DER4 Antibody;Anti-FIT-1 Antibody;Anti-IL1RL1 Antibody;Anti-IL33R Antibody;Anti-IL‑1 R4 Antibody;Anti-ST2 Antibody;Anti-ST2L Antibody;Anti-ST2V Antibody;Anti-T1 Antibody
ST2 Background Information

IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.

Full Name
interleukin 1 receptor-like 1
  • Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
  • Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ST2 Antibody Rabbit Polyclonal ELISA 51143-RP01
    Anti-ST2 Antibody Rabbit Polyclonal WB,ELISA 51143-T48
    Anti-ST2 Antibody Rabbit Monoclonal ELISA 51143-R006
    Anti-ST2 Antibody Rabbit Monoclonal ELISA 10105-R003
    Anti-ST2 Antibody Rabbit Polyclonal ELISA 10105-RP03
    Anti-ST2 Antibody Rabbit Polyclonal ELISA 10105-T16
    Anti-ST2 Antibody Mouse Monoclonal ELISA(Det) 10105-MM12
    Anti-ST2 Antibody Rabbit Polyclonal WB,ELISA 10105-RP01
    Anti-ST2 Antibody Mouse Monoclonal ELISA(Cap) 10105-MM10
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