Anti-IL13RA2 Antibody (Rabbit Monoclonal antibody) General Information
Reacts with: Mouse
Mouse IL13RA2 Has cross-reactivity in ELISA with Human IL13RA2 / CD213A2 No cross-reactivity in ELISA with Mouse IL13RA1 / CD213a1 Human CSF2RB / CD131 Human IL4R / IL4Ra / CD124
Less than 10% cross-reactivity in ELISA with Human IL13RA1 / CD213a1
Recombinant Mouse IL13RA2 protein (Catalog#50061-M08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL13RA2 (Catalog#50061-M08H; NP_032382.1; Met 1-Lys 334).
Monoclonal Rabbit IgG Clone #15
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-IL13RA2 Antibody: Alternative Names
IL13RA2 Background Information
Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 8% of High Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
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