All IL4R reagents are produced in house and quality controlled, including 14 IL4R Antibody, 1 IL4R ELISA, 16 IL4R Gene, 5 IL4R Lysate, 5 IL4R Protein, 2 IL4R qPCR. All IL4R reagents are ready to use.
Recombinant IL4R proteins are expressed by HEK293 Cells with fusion tags as C-His, C-His & C-human IgG1-Fc, C-human IgG1-Fc.
IL4Rantibodies are validated with different applications, which are WB, ELISA, FCM, Neutralization.
IL4RcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL4R of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL4RELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD124, also known as interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.