快速訂購

IL-11 / interleukin 11  Protein, Antibody, ELISA Kit, cDNA Clone

表達宿主: E. coli  
12225-HNCE-50
12225-HNCE-5
12225-HNCE-20
12225-HNCE-10
50 µg 
5 µg 
20 µg 
10 µg 
Add to Cart
  • Slide 1
  • Slide 1
表達宿主: E. coli  
50117-MNCE-50
50117-MNCE-5
50117-MNCE-100
50117-MNCE-10
50 µg 
5 µg 
100 µg 
10 µg 
Add to Cart
  • Slide 1

IL-11 / interleukin 11 相关研究领域

IL-11 / interleukin 11 相關信號通路

    IL-11 / interleukin 11 相關蛋白、抗體、cDNA基因、ELISA試劑盒

    IL-11 / interleukin 11 概述&蛋白信息

    IL-11 / interleukin 11 研究背景

    亞單位結構: Interacts with IL6ST and either IL11RA1 or IL11RA2, giving rise to a multimeric signaling complex. {ECO:0000269|PubMed:12919066, ECO:0000305|PubMed:12919066}.
    亞細胞定位: Secreted {ECO:0000269|PubMed:1828438, ECO:0000269|PubMed:2145578}.
    相似的序列: Belongs to the IL-6 superfamily. {ECO:0000305}.
    General information above from UniProt

    IL11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

    IL-11 / interleukin 11 別稱

    AGIF,IL-11, [homo-sapiens]
    interleukin 11,IL11,AGIF,IL-11,adipogenesis inhibitory factor,oprelvekin, [human]
    interleukin 11,Il11,IL-11, [mouse]
    IL-11, [mus-musculus]

    IL-11 / interleukin 11 相關文獻

  • McKinley D. et al., 1992, Genomics. 13 (3): 814-9.
  • Paul SR. et al., 1990, Proc Natl Acad Sci. 87 (19): 7512-6.
  • Kawashima I. et al., 1991, FEBS Lett. 283 (2): 199-202.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”