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IFNA4  Protein, Antibody, ELISA Kit, cDNA Clone

表達宿主: Yeast  
10336-H08Y-20
10336-H08Y-100
20 µg 
100 µg 
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表達宿主: Baculovirus-Insect Cells  
10336-H08B-50
10336-H08B-20
10336-H08B-100
50 µg 
20 µg 
100 µg 
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表達宿主: Human Cells  
10336-H01H-50
10336-H01H-5
10336-H01H-100
50 µg 
5 µg 
100 µg 
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表達宿主: Human Cells  
50672-M08H-5
50672-M08H-20
50672-M08H-100
5 µg 
20 µg 
100 µg 
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描述: Active  
表達宿主: Human Cells  
50672-M01H-50
50672-M01H-5
50672-M01H-100
50 µg 
5 µg 
100 µg 
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描述: Active  
表達宿主: Human Cells  
80173-R01H-5
80173-R01H-20
80173-R01H-100
5 µg 
20 µg 
100 µg 
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表達宿主: Human Cells  
90851-C05H-50
90851-C05H-5
90851-C05H-100
50 µg 
5 µg 
100 µg 
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表達宿主: Human Cells  
90134-C05H-50
90134-C05H-5
90134-C05H-100
50 µg 
5 µg 
100 µg 
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IFNA4 相关研究领域

IFNA4 相關信號通路

    IFNA4 相關蛋白、抗體、cDNA基因、ELISA試劑盒

    IFNA4 概述&蛋白信息

    IFNA4 研究背景

    亞細胞定位: Secreted.
    相似的序列: Belongs to the alpha/beta interferon family. {ECO:0000305}.
    General information above from UniProt

    Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.

    IFNA4 別稱

    IFNA4, [Cynomolgus]
    INFA4, [Human]
    RP23-139P14.30-001, [Mouse]
    IFNA4, [Rat]

    IFNA4 相關文獻

  • Lau JY, et al. (1993) Discrepancy between biochemical and virological responses to interferon-alpha in chronic hepatitis C. Lancet. 342(8881): 1208-9.
  • Kessler DS, et al. (1990) Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4(10): 1753-65.
  • Gutterman JU. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci U S A. 91(4): 1198-205.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”