输入关键词搜索之后,可以在左侧选择分子或者产品类型以精简过滤器,快速查找产品。如果有任何问题,请 联系我们!

快速訂購

Text Size:AAA

人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-HA 標籤

產品資料評論相關產品實驗方法
Human PMM2 cDNA Clone產品資訊
註冊碼:BC008310
cDNA基因長度:741bp
cDNA基因描述:Full length Clone DNA of Homo sapiens phosphomannomutase 2 with N terminal HA tag.
基因別名:PMI, CDG1, CDGS, PMI1, CDG1a, PMM 2
分子種屬:Human
載體:pCMV3-N-HA
Plasmid:
限制性酶切位點:
Tag序列:HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
序列資訊:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
運輸條件:Each tube contains lyophilized plasmid.
儲存方法:The lyophilized plasmid can be stored at room temperature for three months.
HA Tag Info

Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.

The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.

人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-HA 標籤 on other vectors
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-GFPSpark 標籤HG14648-ACGNT$8150
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-OFPSpark 標籤HG14648-ACRNT$8150
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-GFPSpark 標籤HG14648-ANGNT$8150
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-OFPSpark 標籤HG14648-ANRNT$8150
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-Flag 標籤HG14648-CFNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-His 標籤HG14648-CHNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-Myc 標籤HG14648-CMNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), C-HA 標籤HG14648-CYNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF(克隆載體)HG14648-GNT$2720
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-Flag 標籤HG14648-NFNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-His 標籤HG14648-NHNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-Myc 標籤HG14648-NMNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體), N-HA 標籤HG14648-NYNT$7060
人 phosphomannomutase 2 / PMM2 / CDG1 基因全長cDNA ORF克隆 (表達載體)HG14648-UTNT$7060
 點擊瞭解更多載體資訊
Product nameProduct name
研究背景

Phosphomannomutase 2, also known as PMM2 and CDG1, belongs to the eukaryotic PMM family. Phosphomannomutase 2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. GDP-mannose can transfer its small sugar molecule called mannose to the growing oligosaccharide chain. Once the correct number of small sugar molecules are linked together to form the oligosaccharide, it can be attached to a protein. Phosphomannomutase 2 is also required for a number of critical mannosyl transfer reactions. Mutations in PMM2 gene have been shown to cause defects in the protein glycosylation pathway manifest as carbohydrate-deficient glycoprotein syndrome type I.

參考資料
  • Jaeken J. et al., 2002, Annual review of genomics and human genetics. 2: 129-51.
  • Matthijs G. et al., 2000, Mol Genet Metab. 68 (2): 220-6.
  • Matthijs G. et al., 1997, Nat Genet. 16 (1): 88-92.
  • Size / Price
    貨號: HG14648-NY
    目錄價: 
    單價:      (You Save: )
    規格:
    數量:+-
    庫存2-3 weeks
    大包裝查詢加入購物車
    Contact Us
    產品圖片
        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
        請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”