IL-6 ELISA Kit, Human
Solid Phase Sandwich ELISA (quantitative)
Detection antibody conjugate
Recognizes both recombinant and natural Human IL-6
Preparations of the following factors at 100 ng/mL in a mid-range recombinant
human IL6 control were assayed for interference. No significant interference was observed.
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
This IL-6 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-6 protein in Cell supernatant . It contains recombinant Human IL-6, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
This ELISA Kit is shipped at ambient temperature.
Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA
BSF2 ELISA Kit, Human;HGF ELISA Kit, Human;HSF ELISA Kit, Human;IFNB2 ELISA Kit, Human;IL-6 ELISA Kit, Human;Interleukin-6 ELISA Kit, Human
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Heinrich PC. et al. (2003). Principles of interleukin-6-type cytokine signalling and its regulation. Biochem J. 374: 1-20. Rose-John S, et al. (2007) The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets. 11(5): 613-24. Dinh W, et al. (2009) Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. Cardiovasc Diabetol. 8:58.