输入关键词搜索之后,可以在左侧选择分子或者产品类型以精简过滤器,快速查找产品。如果有任何问题,请 联系我们!

快速訂購

Text Size:AAA

人 IGF-1 / IGF-I / IGF1 蛋白

產品資料評論相關產品實驗方法
Human IGF1 蛋白產品資訊
分子別稱:IGF-1,IGF-I,IGF1A,IGFI,IGF‑I,MGF
蛋白構建:A DNA sequence encoding the human IGF1 (NP_001104754.1) (Gly49-Ala118) was expressed.
分子種屬:Human
表達宿主:Yeast
#N/A:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human IGF1 蛋白質控檢測
純度:> 95 % as determined by SDS-PAGE
生物活性:Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 9-36 ng/mL.
內毒素:Please contact us for more information.
穩定性:Samples are stable for up to twelve months from date of receipt at -70℃
預測N端:Gly 49
分子量:The recombinant human IGF1 consists 70 amino acids and predicts a molecular mass of 7.7 kDa.
緩衝液:Lyophilized from sterile PBS,pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human IGF1 蛋白使用指導
儲存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
#N/A:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human IGF1 Protein SDS-PAGE
Human IGF-1 / IGF-I / IGF1 Protein

IGF1 相關信號通路

    Other IGF1 Recombinant Protein Products
    IGF1/IGF‑I/IGF-1 研究背景

    IGF I, also known as mechano growth factor, somatomedin-C, IGF-I and IGF1, is a secreted protein which belongs to the?insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ) and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.

    Product nameProduct name
    Size / Price
    貨號: 10598-HNAY-100
    目錄價: 
    單價:      (You Save: )
    Contact Us
    產品圖片
    • Human IGF-1 / IGF-I / IGF1 Protein
      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”