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人 IBA1/AIF1 基因全長cDNA ORF克隆 (表達載體)

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 AIF1 cDNA Clone產品資訊
註冊碼:BC009474
cDNA基因長度:444bp
cDNA基因描述:Full length Clone DNA of Homo sapiens allograft inflammatory factor 1.
基因別名:DADB-70P7.8, AIF-1, IBA1, IRT-1, IRT1, AIF1
分子種屬:Human
載體:pCMV3-untagged
Plasmid:pCMV3-AIF1
限制性酶切位點:KpnI + XbaI (6.1kb + 0.44kb)
Tag序列:
序列資訊:Identical with the Gene Bank Ref. ID sequence.
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
( We provide with AIF1 qPCR primers for gene expression analysis, HP102877 )
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Ampicillin
Antibiotic in mammalian cell:Hygromycin
運輸條件:Each tube contains lyophilized plasmid.
儲存方法:The lyophilized plasmid can be stored at room temperature for three months.
 AIF1 Gene Plasmid Map
Human AIF1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
Product nameProduct name
研究背景

AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

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貨號: HG14227-UT
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  • Human AIF1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”