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HSPA5  Protein, Antibody, ELISA Kit, cDNA Clone

HSPA5 相关研究领域

HSPA5 相關信號通路

    HSPA5 概述&蛋白信息

    HSPA5 研究背景

    亞單位結構: Interacts with DNAJC1 (via J domain) (By similarity). Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with TMEM132A and TRIM21. May form a complex with ERLEC1, OS9, SEL1L and SYVN1. Interacts with DNAJC10 and MX1. Interacts with METTL23. Interacts with CEMIP; the interaction induces calcium leakage from the endoplamic reticulum and cell migration. {ECO:0000250, ECO:0000269|PubMed:12411443, ECO:0000269|PubMed:12699405, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18502753, ECO:0000269|PubMed:23349634, ECO:0000269|PubMed:23769672, ECO:0000269|PubMed:23990668}.
    亞細胞定位: Endoplasmic reticulum lumen. Melanosome. Cytoplasm {ECO:0000250}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    相關疾病 : DISEASE: Note=Autoantigen in rheumatoid arthritis. {ECO:0000269|PubMed:11160188}.
    相似的序列: Belongs to the heat shock protein 70 family. {ECO:0000305}.
    General information above from UniProt

    HSPA5 別稱

    BIP,MIF2,GRP78,HEL-S-89n, [homo-sapiens]
    Bip,Sez7,mBiP,Grp78,SEZ-7,Hsce70,baffled,AL022860,AU019543,D2Wsu17e,D2Wsu141e, [mus-musculus]

    HSPA5 相關文獻

    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”