All c-MET reagents are produced in house and quality controlled, including 25 c-MET Antibody, 1 c-MET ELISA, 52 c-MET Gene, 10 c-MET Lysate, 10 c-MET Protein, 3 c-MET qPCR. All c-MET reagents are ready to use.
Recombinant c-MET proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells with fusion tags as C-His, N-GST & His, C-human IgG1-Fc, C-cleavage, C-human IgG1-Fc & His.
c-METantibodies are validated with different applications, which are ELISA, IHC-P, FCM, ELISA(Cap), WB, Neutralization.
c-METcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each c-MET of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
c-METELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Expression host: Baculovirus-Insect Cells
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that has been shown to be overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.