快速訂購

膠質細胞源性神經營養因數(GDNF)

Glial cell line-Derived Neurotrophic Factor (GDNF)

Product CategoriesProteinsAntibodiesELISA KitscDNA Clones
Number of Products

膠質細胞源性神經營養因數(GDNF) Related Products Index

    膠質細胞源性神經營養因數(GDNF) Related Products by Product Type

    膠質細胞源性神經營養因數(GDNF) By Species

    膠質細胞源性神經營養因數(GDNF) by Signaling Pathways

    膠質細胞源性神經營養因數(GDNF) Background

    Glial cell line-derived neurotrophic factor (GDNF) and its three relatives constitute the GDNF family ligands. Other members of the GDNF family are neurturin, artemin and persephin. The GDNF family ligands belong to the TGF-beta superfamily, and share a similar conformation with other members of the TGF-beta superfamily. However, proteins of the GDNF family do not signal through TGF-beta receptors. They signal through a multimolecular protein complex that includes the RET receptor tyrosine kinase and receptors of the GFR-alpha family. NCAM may also act as a GDNF family receptor. These neurotrophic factors are essential for the development of a diverse set of neuronal populations, and have been shown to play a role in a number of biological processes including cell survival, cell differentiation and cell migration.

    膠質細胞源性神經營養因數(GDNF) References