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Galectin-9/LGALS9  Protein, Antibody, ELISA Kit, cDNA Clone

Galectin-9/LGALS9 相关研究领域

Galectin-9/LGALS9 相關信號通路

    Galectin-9/LGALS9 概述&蛋白信息

    Galectin-9/LGALS9 研究背景

    亞單位結構: Monomer. {ECO:0000305|PubMed:18005988, ECO:0000305|Ref.12}.
    結構域: Contains two homologous but distinct carbohydrate-binding domains.
    亞細胞定位: Cytoplasm {ECO:0000250}. Secreted {ECO:0000250}. Note=May also be secreted by a non-classical secretory pathway. {ECO:0000250}.
    組織特異性: Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue.
    相似的序列: Contains 2 galectin domains. {ECO:0000255|PROSITE-ProRule:PRU00639}.
    General information above from UniProt

    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

    Immune Checkpoint
    Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

    Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Galectin-9/LGALS9 別稱

    Galectin-9/LGALS9 相關文獻

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