Anti-GAPDH Antibody

Cat: 100242-R005
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All GAPDH Reagents
Anti-GAPDH Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-GAPDH Antibody
Validated applications
Species reactivity
Reacts with: Human
A synthetic peptide corresponding to the center region of the human GAPDH
This antibody was obtained from a rabbit immunized with A synthetic peptide corresponding to the center region of the human GAPDH.
Monoclonal Rabbit IgG Clone #005
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-GAPDH Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
IHC-P 1:100-1:500  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-GAPDH Antibody (Rabbit Monoclonal antibody) Images
Human GAPDH Immunohistochemistry(IHC) 4167
Immunochemical staining of human GAPDH in human hepatitis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Human GAPDH Immunohistochemistry(IHC) 18963
Immunochemical staining of human GAPDH in human appendicitis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Anti-GAPDH Antibody Alternative Names
Anti-G3PD Antibody;Anti-GAPD Antibody;Anti-HEL-S-162eP Antibody
GAPDH Background Information

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.

Full Name
glyceraldehyde-3-phosphate dehydrogenase
  • Hara MR, et al. (2006) Neuroprotection by pharmacologic blockade of the GAPDH death cascade. PNA. 103 (10): 3887-9.
  • Hara MR, et al. (2006) GAPDH as a sensor of NO stress.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1762 (5): 502-9.
  • Tarze A, et al. (2007) GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilizationGAPDH and apoptosis. Oncogene. 26: 2606-20.
  • Yi MK, et al. (2000) Functional Significance of the Interaction of Hepatitis A Virus RNA with Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH): Opposing Effects of GAPDH and Polypyrimidine Tract Binding Protein on Internal Ribosome Entry Site Function. Journal of Virology. 74 (14) : 6459-68.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-GAPDH Antibody Mouse Monoclonal WB 100242-MM05
    Anti-GAPDH Antibody Rabbit Polyclonal WB,ELISA,IP 10094-T52
    Anti-GAPDH Antibody Rabbit Polyclonal IHC-P 100242-T08
    Anti-GAPDH Antibody Rabbit Polyclonal WB,IHC-P 100242-T40
    Anti-GAPDH Antibody Rabbit Polyclonal ELISA 10094-T16
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