快速訂購

留言    收藏

GAPDH 抗體, 兔多抗, 抗原親和純化

  • GAPDH Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • GAPDH Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • GAPDH Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
產品資料評論相關產品實驗方法
 GAPDH 抗體產品資訊
免疫原:A synthetic peptide corresponding to the center region of the human GAPDH
Clone ID:
Ig類型:Rabbit IgG
濃度:
內毒素:
緩衝液:0.2 μm filtered solution in PBS
抗體製備方法:Produced in rabbits immunized with A synthetic peptide corresponding to the center region of the human GAPDH, and purified by antigen affinity chromatography.
 GAPDH Antibody WB Application Image
 GAPDH Antibody IHC Application Image
GAPDH Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[點擊查看大圖]
Caption:
Immunochemical staining of human GAPDH in human breast carcinoma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
GAPDH Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[點擊查看大圖]
Caption:
Immunochemical staining of human GAPDH in human renal carcinoma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other GAPDH Antibody Products
GAPDH 研究背景

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.

 GAPDH 參考資料
  • Hara MR, et al. (2006) Neuroprotection by pharmacologic blockade of the GAPDH death cascade. PNA. 103 (10): 3887-9.
  • Hara MR, et al. (2006) GAPDH as a sensor of NO stress.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1762 (5): 502-9.
  • Tarze A, et al. (2007) GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilizationGAPDH and apoptosis. Oncogene. 26: 2606-20.
  • Yi MK, et al. (2000) Functional Significance of the Interaction of Hepatitis A Virus RNA with Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH): Opposing Effects of GAPDH and Polypyrimidine Tract Binding Protein on Internal Ribosome Entry Site Function. Journal of Virology. 74 (14) : 6459-68.
  • Product nameProduct name
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”