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大鼠 Ephrin-B3 / EFNB3 蛋白 (Fc 標籤)

  • Rat Ephrin-B3 / EFNB3 Protein (Fc Tag) SDS-PAGE
產品資料評論相關產品實驗方法
大鼠 EFNB3 蛋白產品資訊
分子別稱:EFNB3
蛋白構建:A DNA sequence encoding the rat EFNB3 (NP_001094450) (Met1-Ser224) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
分子種屬:Rat
表達宿主:Human Cells
#N/A:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
大鼠 EFNB3 蛋白質控檢測
純度:(79.6+17) % as determined by SDS-PAGE
生物活性:Measured by its binding ability in a functional ELISA.
Immobilized mouse EphB3-His (Cat:50581-M08H) at 10 μg/ml (100 μl/well) can bind rat EFNB3-Fc, The EC50 of rat EFNB3-Fc is 14.1-33.2 ng/ml.
內毒素:< 1.0 EU per μg of the protein as determined by the LAL method
穩定性:Samples are stable for up to twelve months from date of receipt at -70℃
預測N端:Leu 28
分子量:The recombinant rat EFNB3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 438 amino acids and has a predicted molecular mass of 48.7 kDa. The apparent molecular mass of the protein is approximately 55 and 34 kDa in SDS-PAGE under reducing conditions.
緩衝液:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
大鼠 EFNB3 蛋白使用指導
儲存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
#N/A:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
大鼠 EFNB3 Protein SDS-PAGE
Rat Ephrin-B3 / EFNB3 Protein (Fc Tag) SDS-PAGE

EFNB3 相關信號通路

    Other EFNB3 Recombinant Protein Products
    80112-R02H
    Ephrin B3 / EFNB3 研究背景

    Ephrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.

    大鼠 Ephrin B3 / EFNB3 參考資料
  • Takemoto M, et al. (2002) Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro. Eur J Neurosci. 16(6):1168-72.
  • Brckner K, et al. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 22(3):511-24.
  • Bergemann A, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4):471-80.
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    Size / Price
    貨號: 80112-R02H-50
    目錄價: 
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”