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claudin 1/CLDN1  Protein, Antibody, ELISA Kit, cDNA Clone

claudin 1/CLDN1 相关研究领域

claudin 1/CLDN1 相關信號通路

    claudin 1/CLDN1 概述&蛋白信息

    claudin 1/CLDN1 研究背景

    亞單位結構: Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL (By similarity). Can form homo- and heteropolymers with other claudin family members. May interact with HCV E1 and E2 proteins. {ECO:0000250, ECO:0000269|PubMed:17325668, ECO:0000269|PubMed:23704991}.
    亞細胞定位: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
    組織特異性: Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. {ECO:0000269|PubMed:9931503}.
    相關疾病 : DISEASE: Ichthyosis-sclerosing cholangitis neonatal syndrome (NISCH) [MIM:607626]: A rare autosomal recessive complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, mild diffuse ichthyosis, sclerosing cholangitis and leukocyte vacuolization. {ECO:0000269|PubMed:15521008, ECO:0000269|PubMed:16619213}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    相似的序列: Belongs to the claudin family. {ECO:0000305}.
    General information above from UniProt

    claudin 1/CLDN1 別稱

    CLD1,SEMP1,ILVASC, [homo-sapiens]
    AI596271, [mus-musculus]

    claudin 1/CLDN1 相關文獻

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