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Properdin  Protein, Antibody, ELISA Kit, cDNA Clone

Properdin 相关研究领域

Properdin 相關信號通路

    Properdin 概述&蛋白信息

    Properdin 研究背景

    亞單位結構: In plasma, properdin exists as dimers, trimers or tetramers in the relative proportions of 26:54:20. {ECO:0000269|PubMed:15491616, ECO:0000269|PubMed:20382442}.
    結構域: TSP type-1 domains 0 and 6 bind to each other and mediate multimerization.
    亞細胞定位: Secreted.
    相關疾病 : DISEASE: Properdin deficiency (PFD) [MIM:312060]: Results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). {ECO:0000269|PubMed:10909851, ECO:0000269|PubMed:8871668, ECO:0000269|PubMed:9710744}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    相似的序列: Contains 7 TSP type-1 domains. {ECO:0000255|PROSITE-ProRule:PRU00210}.
    General information above from UniProt

    Properdin 別稱

    PFC,PROPERDIN,BFD,PFD, [homo-sapiens]
    Pfc,BCFG, [mus-musculus]

    Properdin 相關文獻

    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”