快速訂購

CDKL2  Protein, Antibody, ELISA Kit, cDNA Clone

CDKL2 相关研究领域

CDKL2 相關信號通路

    CDKL2 概述&蛋白信息

    CDKL2 研究背景

    基因概述: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.
    General information above from NCBI
    催化活性: ATP + a protein = ADP + a phosphoprotein.
    結構域: The [NKR]KIAxRE motif seems to be a cyclin-binding region.
    亞細胞定位: Cytoplasm {ECO:0000269|PubMed:9000130}. Nucleus {ECO:0000269|PubMed:9000130}.
    組織特異性: Expressed in testis and kidney, and at lower level in brain and lung. {ECO:0000269|PubMed:9000130}.
    相似的序列: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. {ECO:0000305}.; Contains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
    General information above from UniProt

    Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.

    CDKL2 別稱

    P56,KKIAMRE, [homo-sapiens]
    CDKL2,KKIAMRE,P56, [human]
    5330436L21Rik,AI505225,KKIAMRE,Kkm,MGC144031,MGC144032,Cdkl2, [mouse]
    Kkm,KKIAMRE,AI505225,5330436L21Rik, [mus-musculus]

    CDKL2 相關文獻

  • Sassa T, et al. (2003) Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus. Cell and Tissue Research. 315 (2): 147-56.
  • Rosenblatt J, et al. (1992) Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. PNAS. 89 (7): 2824-8.
  • Mironov V, et al. (1999) Cyclin-Dependent Kinases and Cell Division in Plants-The Nexus. The Plant Cell. 11 (4): 509-22.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”