CD31 (Protein | Antibody | cDNA Clone | ELISA Kit)

All CD31 reagents are produced in house and quality controlled, including 27 CD31 Antibody, 2 CD31 ELISA, 53 CD31 Gene, 2 CD31 IP Kit, 4 CD31 Lysate, 4 CD31 Protein, 3 CD31 qPCR. All CD31 reagents are ready to use.

CD31 Protein (4)

CD31 Antibody (27)

CD31 ELISA Kit & Match Antibody ELISA Pair Set (2)

CD31 cDNA Clone (53)

NM_000442.3
NM_000442.4

In expression vector

NM_001305157.1
NM_031591.1
XM_001116542.2

CD31 Lysate (4)

CD31 Background

The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 13-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.

CD31 References

  • Deaglio S, et al. (2000) CD38/CD31, a receptor/ligand system ruling adhesion and signaling in human leukocytes. Chem Immunol. 75: 99-120.
  • Kohler S, et al. (2009) Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets. Blood. 113(4): 769-74.