RON (Protein|Antibody|cDNA Clone|ELISA Kit)

All RON reagents are produced in house and quality controlled, including 8 RON Antibody, 1 RON Gene, 1 RON Lysate, 1 RON Protein, 1 RON qPCR. All RON reagents are ready to use.

Recombinant RON proteins are expressed by HEK293 Cells with fusion tags as C-His.

RONantibodies are validated with different applications, which are FCM, ELISA, IHC-P.

RONcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each RON of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

RON Protein (1)

Species

RON Protein, Human, Recombinant (His Tag)

11608-H08H

Expression host: HEK293 Cells

Human CD136/MST1R Protein 9644
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RON Antibody (8)

Application Clonality
Host

Anti-RON Antibody

11608-T24

Application: ELISA,IHC-P

Clonality: PAb

Human CD136/MST1R Immunohistochemistry(IHC) 17430

Anti-RON Antibody

11608-RP02

Application: ELISA

Clonality: PAb

Anti-RON Antibody

11608-MM03

Application: FCM

Clonality: MAb

Human CD136/MST1R Flow Cytometry (FC) 17514

Anti-RON Antibody (FITC)

11608-MM03-F

Application: FCM

Clonality: MAb

Human CD136/MST1R Flow Cytometry (FC) 17617

Anti-RON Antibody

11608-MM04

Application: ELISA

Clonality: MAb

Anti-RON Antibody

102358-T08

Application: IHC-P

Clonality: PAb

Mouse CD136/MST1R Immunohistochemistry(IHC) 15213

Anti-RON Antibody

11608-MM02

Application: ELISA

Clonality: MAb

Anti-RON Antibody (PE)

11608-MM03-P

Application: FCM

Clonality: MAb

Human CD136/MST1R Flow Cytometry (FC) 17623
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RON cDNA Clone (1)

Cynomolgus

RON qPCR Primer (1)

RON Lysate (1)

The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As tyrosine kinase receptor comprised of an extra-cellular domain, MST1R protein contains the ligand binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in vivo during injury. This assessment of gene expression indicates the importance of genetic factors in contributing to lung injury, and points to strategies for intervention in the progression of inflammatory diseases. It had been shown that MST1R/CD136 plays a critical role in Ni-induced lung injury in mice. The overexpression of MSP, MT-SP1, and MST1R was a strong independent indicator of both metastasis and death in human breast cancer patients and significantly increased the accuracy of an existing gene expression signature for poor prognosis. Stimulation of MST1R leads to its transphosphorylation and the ultimate activation of numerous intracellular signaling pathways, such as the classical mitogen-activated protein kinase pathway, the phosphotidylinositol (PI)3-kinase pathway, and the JNK pathway.

Protein
Antibody
Gene
qPCR
Lysate
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