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恒河猴 CCL17 / TARC 蛋白 (His 標籤)

  • Rhesus CCL17 / TARC Protein (His Tag)
產品資料評論相關產品實驗方法
恒河猴 CCL17/TARC 蛋白產品資訊
分子別稱:CCL17, TARC
蛋白構建:A DNA sequence encoding the rhesus CCL17 (Q8HYP9) (Met1-Ser94) was expressed with a polyhistidine tag at the C-terminus.
分子種屬:Rhesus
表達宿主:Baculovirus-Insect Cells
#N/A:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
恒河猴 CCL17/TARC 蛋白質控檢測
純度:> 95 % as determined by SDS-PAGE
內毒素:< 1.0 EU per μg of the protein as determined by the LAL method
穩定性:Samples are stable for up to twelve months from date of receipt at -70℃
預測N端:Ala 24
分子量:The recombinant rhesus CCL17 comprises 81 amino acids and has a calculated molecular mass of 9.5 KDa.
緩衝液:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
恒河猴 CCL17/TARC 蛋白使用指導
儲存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
#N/A:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
恒河猴 CCL17/TARC Protein SDS-PAGE
Rhesus CCL17 / TARC Protein (His Tag)

CCL17/TARC 相關信號通路

    Other CCL17/TARC Recombinant Protein Products
    90077-C08B
    CCL17/TARC 研究背景

    Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

    恒河猴 CCL17/TARC 參考資料
  • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
  • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
  • Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1-2): 67-75.
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    貨號: 90077-C08B-20
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        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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