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CAMKV  蛋白

All CAMKV Reagents

表達宿主: Baculovirus-Insect Cells  
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12243-H20B-20
12243-H20B-50
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50 µg 
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CAMKV 相關信號通路

CAMKV 概述&蛋白信息

CAMKV 研究背景

基因概述: OMIM - description for CAMKV:
General information above from NCBI
輔因數: Calcium (By similarity).
亞單位結構: Interacts with calmodulin, in the presence of calcium (By similarity).
結構域: The protein kinase domain is predicted to be catalytically inactive.
亞細胞定位: Cell membrane; Peripheral membrane protein (By similarity). Cytoplasmic vesicle membrane; Peripheral membrane protein (By similarity). Note=Predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. May be associated with vesicular structures (By similarity).
相似的序列: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain.C
General information above from UniProt

CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. CAMKV contains one protein kinase domain. It is predominantly observed in association with the plasma membrane of soma and in neurites, both axons and dendrites. CAMKV may be associated with vesicular structures. It does not appear to have detectable kinase activity.

Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. Protein kinases function as an on/off switch for many cellular processes, including metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. They also function in embryonic development, physiological responses, and in the nervous and immune system. Abnormal phosphorylation causes many human diseases, including cancer, and drugs that affect phosphorylation can treat those diseases. The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins.

CAMKV 別稱

1G5,VACAMKL, [homo-sapiens]
1G5,MGC8407,CAMKV,VACAMKL, [human]
1G5,BB074618,BC017634,Camkv,MGC118008,MGC28873, [mouse]
1G5,BB074618,BC017634, [mus-musculus]

CAMKV 相關文獻

  • Hunter T, et al.,1988, Science. 241 (4861): 42-51.
  • Wiemann S., et al., 2001, Genome Res. 11:422-435.
  • G. Manning, et al., 2002, Science 6. 298:1912-1934.
  • Manning G, et al.,2002, Science. 298 (5600): 1912-34.
  • Ota T., et al., 2004, Nat. Genet. 36:40-45.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”