Biological Target Antibody

Biological Target Antibody-Human Target

• Human IL1R2 / IL1RB / CD121b Antibody • Human VEGFR3 / FLT4 Antibody
• Human IL1R1 / CD121a Antibody • Human HER3 / ErbB3 Antibody
• Human CSF1R / M-CSFR / CD115 Antibody • Human Cadherin-1 / CDH1 / E-cadherin Antibody
• Human IGF1R / CD221 Antibody • Human TNF-beta / Lymphotoxin alpha Antibody
• Human IL6R / CD126 Antibody • Human MMP9 / CLG4B Antibody
• Human FGFR4 / CD334 Antibody • Human Osteopontin / SPP1 / OPN Antibody
• Human FGFR1 / CD331 Antibody • Human PD1 / PDCD1 / CD279 Antibody
• Human HGFR / c-MET Antibody  

Biological Target Antibody-Mouse Target

• Mouse PD-L1 / B7-H1 / CD274 Antibody • Mouse Fetuin-A / AHSG Antibody
• Mouse B7-H1 / CD274 / PD-L1 Antibody • Mouse Oncostatin M / OSM Antibody
• Mouse Carbonic Anhydrase XIV / CA14 Antibody • Mouse PD1 / PDCD1 / CD279 Antibody
• Mouse CA14 protein Antibody • Mouse AXL / UFO Antibody
• Mouse CD95 / APO-1 / TNFRSF6 / FAS Antibody • Mouse TNFR2 / CD120b / TNFRSF1B Antibody
• Mouse SELL / CD62L / L-selectin Antibody • Mouse MSR1 / CD204 Antibody
• Mouse CSF1R / MCSF Receptor / CD115 Antibody • Mouse VEGF / VEGFA / VEGF165 Antibody
• Mouse IL11RA / IL11Rα Antibody  

Biological Target Antibody-Rat Target

• Rat VEGF / VEGFA / VEGF165 Antibody • Rat VEGFR2 / Flk-1 / CD309 / KDR Antibody
• Rat CNTFR Antibody • Rat IL13RA2 / IL13R Antibody
• Rat GM-CSF / CSF2 Antibody • Rat Cadherin-5 / CDH5 / VE-Cad Antibody
• Rat ICAM-1 / CD54 Antibody • Rat ADAM17 Antibody
• Rat CRP / C-Reactive Protein Antibody • Rat B7-H3 / CD276 Antibody
• Rat FAS / TNFRSF6 / CD95 Antibody • Rat HGF / Hepatocyte Growth Factor Antibody
• Rat CD95 / APO-1 / TNFRSF6 Antibody • Rat CTLA-4 / CD152 Antibody
• Rat HER2 / ErbB2 Antibody  

Biological Target Antibody-Other Species

• Rhesus HER2 / ErbB2 Antibody • Feline IL-10 Antibody
• Rhesus HER3 / ErbB3 Antibody • Feline IL-1 beta Antibody
• Rhesus DKK-1 Antibody • Canine aFGF / FGF1 Antibody
• Ferret TNF-alpha / TNFA Antibody • Canine PD1 / PDCD1 / CD279 Antibody
• Sus scrofa (Pig) IL-10 Antibody • Canine CTLA-4 / CD152 Antibody
• Sus scrofa (Pig) IL-1 beta Antibody • Cynomolgus p53 / TP53 Antibody
• Sus scrofa (pig) IL6 / IL-6 Antibody • Cynomolgus IFN gamma Antibody
• Rabbit CD38 Antibody  

Biological Target Antibody-Mouse monoclonal antibody

• Human Sox2 Antibody • Canine HGFR / c-MET Antibody
• Human Neuropilin-1 / NRP1 / CD304 Antibody • Rat E-Selectin / CD62e / SELE Antibody
• Human IL12A / IL-12A Antibody • Rat VE-Cadherin / CD144 / CDH5 Antibody
• Human 4E-BP1 / EIF4EBP1 Antibody • Cynomolgus CD32a / Fc gamma RIIA Antibody
• Rabbit CD38 Antibody • Cynomolgus IL18 / Interleukin-18 Antibody
• Ferret TNFA / TNF-alpha Antibody • Rhesus HER2 / ErbB2 Antibody
• Ferret CD4 Antibody • Rhesus ErbB3 / HER3 Antibody
• Canine TNF-alpha Antibody  

Biological Target Antibody-Rabbit monoclonal antibody

• Human Bcl-2 Antibody • Ferret CD20 / MS4A1 Antibody
• Human bFGF / FGF2 Antibody • Canine TNF-a / TNF-alpha Antibody
• Human BACE1 / ASP2 Antibody • Canine HGFR / c-MET Antibody
• Human BLyS / TNFSF13B Antibody • Rat VEGF164 / VEGFA Antibody
• Human PD-L1 / B7-H1 / CD274 Antibody • Rat CNTF Antibody
• Mouse Carbonic Anhydrase XIV / CA14 Antibody • Cynomolgus CD32b / Fc gamma RIIB Antibody
• Mouse CD86 / ETC-1 / B7-2 Antibody • Cynomolgus CD32a / Fc gamma RIIA Antibody
• Mouse Fetuin-A / AHSG Antibody  

Biological Target Antibody-Rabbit Polyclonal antibody

• Human VEGF / VEGFA / VEGF165 Antibody • Ferret CD4 Antibody
• Human bFGF / FGF2 Antibody • Ferret TNF-alpha / TNFA Antibody
• Human JAM-A / PAM-1 / CD321 Antibody • Ferret CD20 / MS4A1 Antibody
• Human TrkB / NTRK2 Antibody • Sus scrofa (Pig) IL-1 beta Antibody
• Human CD156a Antibody • Sus scrofa (pig) IL6 / IL-6 Antibody
• Human ITGA6 Antibody • Sus scrofa (Pig) IL-10 Antibody
• Human BACE1 / ASP2 Antibody • Cynomolgus PDGFRB / CD140b Antibody
• Mouse VEGFR2 / Flk-1 / CD309 / KDR Antibody • Cynomolgus EpCAM / TROP-1 / TACSTD1 Antibody
• Mouse TrkA / NTRK1 Antibody • Cynomolgus IL13 / ALRH Antibody
• Mouse CCL3 / Mip1a Antibody • Rhesus DKK-1 Antibody
• Mouse GPA33 Antibody • Rhesus HER2 / ErbB2 Antibody
• Mouse MMP-9 / MMP9 Antibody • Rhesus DKK-1 Antibody
• Rat CRP / C-Reactive Protein Antibody • Feline IL-1 beta Antibody
• Rat CD95 / APO-1 / TNFRSF6 Antibody • Feline IL-10 Antibody
• Rat PRLR Antibody • Canine aFGF / FGF1 Antibody
• Rat CD127 / IL-7RA Antibody • Canine TrkA / NTRK1 Antibody

Biological Target Antibody-Western Blot

• Human MMP-2 / CLG4A Antibody • Rhesus DKK-1 Antibody
• Human Dkk1 / Dickkopf-1 Antibody • Sus scrofa (Pig) IL-10 Antibody
• Human DC-SIGN / CD209 Antibody • Canine IL-1 beta Antibody
• Human Osteopontin / SPP1 / ETA-1 Antibody • Canine Carbonic Anhydrase IX / CA9 Antibody
• Human Cyclophilin A Antibody • Rat CD32b / Fc gamma RIIB Antibody
• Mouse IL6 / IL-6 Antibody • Rat UCHL1 Antibody
• Mouse KLK6 / Kallikrein 6 / Neurosin Antibody • Cynomolgus CCL21 / SCYA21 Antibody
• Mouse Coagulation Factor III / CD142 / F3 Antibody • Cynomolgus SELP / P Selectin Antibody
• Mouse E-Cadherin / CDH1 / E-cad / CD324 Antibody • Cynomolgus IFNAR1 Antibody

Biological Target Antibody-ELISA

• Human VEGF121 / VEGF-A Antibody • Sus scrofa (pig) IL6 / IL-6 Antibody
• Human PD-L1 / B7-H1 / CD274 Antibody • Feline IL-10 Antibody
• Mouse B7-H1 / CD274 / PD-L1 Antibody • Feline IL-1 beta Antibody
• Mouse FVII / Factor VII / F7 Antibody • Canine Carbonic Anhydrase IX / CA9 Antibody
• Rhesus HER3 / ErbB3 Antibody • Canine CTLA-4 / CD152 Antibody
• Rhesus DKK-1 Antibody • Rat IL6ST / gp130 / CD130 Antibody
• Ferret TNFA / TNF-alpha Antibody • Rat ACE2 Antibody
• Ferret CD20 / MS4A1 Antibody • Cynomolgus c-Met / HGFR Antibody
• Sus scrofa (Pig) IL-1 beta Antibody • Cynomolgus FGFR3 / CD333 Antibody

Biological Target Antibody-Immunohistochemistry / IHC

• Human E-cadherin / CDH1 / Cadherin-1 / E-Cad Antibody • Mouse PSGL-1 / CD162 Antibody
• Human Leptin / LEP Antibody • Rat IL13RA2 / IL13R Antibody
• Human ICAM1 / CD54 Antibody • Rat EpCAM / TROP-1 / TACSTD1 Antibody
• Human PD1 / PDCD1 / CD279 Antibody • Rat CD79B Antibody
• Human CX3CL1 / FKN Antibody • Rat Thrombomodulin / THBD Antibody
• Mouse CD38 Antibody • Rat TrkA / NTRK1 Antibody
• Mouse S100A8 Antibody • Cynomolgus p53 / TP53 Antibody
• Mouse REN1 / Renin-1 Antibody • Cynomolgus IL-1 beta Antibody
• Mouse CHK2 / CHEK2 Antibody • Cynomolgus CD32b / Fc gamma RIIB Antibody

Biological Target Antibody-Immunofluorescence / IF

• Human Endoglin / CD105 Antibody • Mouse CD14 Antibody
• Human IGF1R / CD221 Antibody • Mouse CD27 Antibody
• Human CD147 / EMMPRIN / Basigin Antibody • Mouse MSR1 / CD204 Antibody
• Human Leptin / LEP Antibody • Mouse IL-6R / CD126 Antibody
• Human EphB4 Antibody • Mouse LDLR / LDL Receptor Antibody
• Human Tie2 / CD202b / TEK Antibody • Mouse Basigin / BSG / CD147 Antibody
• Human Serum Albumin / HSA Antibody • Mouse LY9 / CD229 / SLAMF3 Antibody
• Human N-Cadherin / CD325 / CDH2 Antibody • Rat ICAM-1 / CD54 Antibody
• Human B7-H3 / CD276 Antibody • Cynomolgus p53 / TP53 Antibody

Biological Target Antibody-Flow Cytometry / FACS

• Human EGFR / HER1 / ErbB1 Antibody • Mouse MSR1 / CD204 Antibody
• Human ErbB2 / HER2 / CD340 Antibody • Mouse IFNGR1 / CD119 Antibody
• Human Neuropilin-1 / NRP1 / CD304 Antibody • Mouse IL-1R1 / CD121a Antibody
• Human 4E-BP1 / EIF4EBP1 Antibody • Mouse PD-L1 / B7-H1 / CD274 Antibody
• Human CD27 / TNFRSF7 Antibody • Mouse CD14 Antibody
• Human CD31 / PECAM-1 Antibody • Mouse CD25 / IL2RA Antibody
• Human IGF1R / CD221 Antibody • Ferret CD4 Antibody
• Human E-Selectin / CD62e Antibody • Rat ICAM-1 / CD54 Antibody
• Mouse TNFR2 / CD120b / TNFRSF1B Antibody • Rat CD40 / TNFRSF5 Antibody

Biological Target Antibody-Immunoprecipitation / IP

• Human Cytokeratin 19 Antibody • Mouse MAP2 / METAP2 Antibody
• Human BLyS / TNFSF13B / BAFF Antibody • Mouse UCHL1 Antibody
• Human Fibronectin Fragment 2 Antibody • Mouse B7-H3 / CD276 Antibody
• Human HSP27 Antibody • Mouse TIM-3 / HAVCR2 Antibody
• Human Osteopontin / SPP1 / ETA-1 Antibody • Mouse LIF Antibody
• Human TGF-beta 1 / TGFB1 Antibody • Canine Carbonic Anhydrase IX / CA9 Antibody
• Human AFP / alpha-fetoprotein Antibody • Rat UCHL1 Antibody
• Human CD69 Antibody • Rat B7-H3 / CD276 Antibody
• Mouse Cathepsin A / CTSA Antibody • Cynomolgus EpCAM / TROP-1 / TACSTD1 Antibody

Biological Target Antibody-Enzyme Target

• Human Thrombopoietin / THPO / TPO Antibody • Human CD10 / Neprilysin / MME Antibody
• Human Tryptophan Hydroxylase 1 / TPH1 Antibody • Human TXNRD1 Antibody
• Human FDPS / Farnesyl Diphosphate Synthase Antibody • Human Renin / REN Antibody
• Human dehydropeptidase-I / DPEP1 Antibody • Human DOPA Decarboxylase / DDC Antibody
• Human Coagulation Factor IX / FIX / F9 Antibody • Human MMP-2 Antibody
• Human Coagulation Factor X / F10 Antibody • Human MMP-3 Antibody
• Human Carbonic Anhydrase XII / CA12 Antibody • Human MMP-9 / CLG4B Antibody
• Human PNLIP Antibody • Mouse BCHE / Butyrylcholinesterase Antibody
• Human PTP1B / PTPN1 Antibody • Mouse Coagulation Factor II / F2 Antibody
• Human KLK1 / Kallikrein 1 Antibody • Mouse TH / Tyrosine Hydroxylase Antibody
• Human Carbonic Anhydrase II / CA2 Antibody • Mouse Acetylcholinesterase / ACHE Antibody
• Human Carbonic Anhydrase IV / CA4 Antibody  

Biological Target Antibody-Receptor Target

• Human CD3e / CD3 epsilon Antibody • Human IGF1R / CD221 Antibody
• Human EPOR Antibody • Human CD80 / B7-1 Antibody
• Human IL1R1 / CD121a Antibody • Human IL6R / CD126 Antibody
• Human IL-1R2 / CD121b Antibody • Mouse IL11RA / IL11Rα Antibody
• Human FGFR2 / CD332 Antibody • Mouse Growth Hormone Receptor / GHR Antibody
• Human FGFR4 / CD334 Antibody • Mouse FGFR3 / CD333 Antibody

Biological Target Antibody-Immunomodulation Target

• Human Complement C5a Antibody • Human IFNAR2 Antibody
• Human CSF2RA / GM-CSFR / CD116 Antibody • Human IFNGR1 / CD119 Antibody (APC)
• Human CD131 / CSF2RB / IL3RB / IL5RB Antibody • Human TNF-alpha / TNFA Antibody
• Human IFNAR1 / IFNAR Antibody  

Biological Target Antibody-Inflammation Target

• Human ALOX15B / 15 Lipoxygenase 2 Antibody • Human IL-1 beta / IL1B / IL1F2 Antibody
• Human FKBP1A / FKBP12 Antibody • Human SerpinA6 Antibody
• Human IL-1 alpha / IL-1F1 / IL1A Antibody  

Biological Target Antibody-Cardiovascular diseases Target

• Human CD10 / Neprilysin / MME Antibody • Human Carbonic Anhydrase II / CA2 Antibody
• Human Renin / REN Antibody • Mouse TH / Tyrosine Hydroxylase Antibody
• Human Carbonic Anhydrase IV / CA4 Antibody  

Biological Target Antibody-Cancer Target

• Human Bcl-2 Antibody • Human MMP-2 Antibody
• Human CD33 / Siglec-3 Antibody • Human MMP-3 Antibody
• Human CSF1R / MCSF Receptor / CD115 Antibody • Human MMP-9 / CLG4B Antibody
• Mouse EphA2 Antibody • Human CD20 / MS4A1 Antibody
• Human HER2 / ErbB2 Antibody • Human TrkA / NTRK1 / TRKA Antibody
• Human VEGFR1 / FLT-1 Antibody • Human PDGFRa / CD140a Antibody
• Human FLT3 / CD135 / FLK2 Antibody (APC) • Human PDGFRB / CD140b Antibody
• Human VEGFR3 / FLT-4 Antibody • Human RET Kinase Antibody
• Human CD25 / IL2RA Antibody • Human TXNRD1 Antibody

Biological Target Antibody-Pathogen Target

• Influenza A H1N1 Hemagglutinin / HA Antibody
• Influenza A H2N2 Hemagglutinin / HA Antibody
• Influenza A H3N2 Hemagglutinin / HA Antibody
• Influenza A H4N6 Hemagglutinin / HA Antibody
• Influenza A H5N3 Hemagglutinin / HA Antibody
• Influenza A H6N1 Hemagglutinin / HA Antibody
• Influenza A H7N7 Hemagglutinin / HA Antibody
• Influenza A H8N4 Hemagglutinin / HA Antibody
• Influenza A H9N2 Hemagglutinin / HA Antibody
• Influenza B Hemagglutinin / HA Antibody
• Influenza A H10N3 Hemagglutinin / HA Antibody
• Influenza A H11N2 Hemagglutinin / HA Antibody
• Influenza A H12N5 Hemagglutinin / HA Antibody
• Influenza A H16N3 Hemagglutinin / HA Antibody
• Influenza A Nucleoprotein / NP Antibody
• Influenza A H3N2 Nucleoprotein / NP Antibody
• Human respiratory syncytial virus (RSV) Fusion Glycoprotein / RSV-F Antibody
• Human respiratory syncytial virus (RSV) Glycoprotein G / RSV-G Antibody
• Human cytomegalovirus (HCMV) Glycoprotein B / gB Antibody
• Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD / Glycoprotein Antibody
• Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein / GP Antibody
• HPV16 L1 Antibody (Conformational Antibody)
• Plasmodium falciparum (strain 3D7) HPRT Antibody
• PfLDH / L-lactate dehydrogenase Antibody
• BirA / Bifunctional protein BirA Antibody
• Escherichia coli ssPA / Stringent starvation protein A Antibody
• Escherichia coli acnB Antibody
• Escherichia coli Enoyl-ACP Reductase / FABI Antibody

Featured Biological Target Proteins

• PD1 PDCD1 CD279 Protein • AKT1 Protein
• PD-L1 B7-H1 CD274 Protein • MAP2K1 Protein
• PD-L2 B7-DC PDCD1LG2 Protein • MAPK1 Protein
• VEGF Protein • SHH Protein
• EGFR Protein • TP53 Protein
• ERBB2 HER2 Protein • CDK4 Protein
• ERBB3 HER3 Protein • ACVR1 Protein
• ERBB4 HER4 Protein • BCL2 Protein

Biological Target Background

Biological target is very critical to drug discovery, drug development and disease diagnosis. Based on published estimates, there are approximately 1100 host biological targets and 200 pathogen biological targets. Among them, about one third is therapeutic affect-mediating target (also known as drug target). According to their funtions in signaling pathways, host biological targets can be classified into receptors, enzymes, transporters, and other molecules. The best-known receptor family is G protein-cou¬pled receptors (GPCRs), followed by receptor tyrosine kinases and ligand-gated ion channels; while the most famous enzyme family is hydrolases, then oxidoreductases and transferases. Pathogen biological targets in Sino Biological mainly come from virus (e.g. influenza virus, HIV, EBOV, coronavirus, RSV, and cytomegalovirus), bacteria (e.g. C. perfringens, Listeria monocytogenes, and M. viridifaciens), and parasite (e.g. plasmodium falciparum). Biological target reagents can be used in pharmaceutical industry and academic biomedical research for immunomodulation, inflammation, cardiovascular diseases, central nervous system (CNS) and cancer etc.

Antibody