All ASGR2 reagents are produced in house and quality controlled, including 3 ASGR2 Antibody, 26 ASGR2 Gene, 1 ASGR2 Lysate, 1 ASGR2 Protein, 1 ASGR2 qPCR. All ASGR2 reagents are ready to use.
Recombinant ASGR2 proteins are expressed by HEK293 Cells with fusion tags as N-His.
ASGR2antibodies are validated with different applications, which are FCM, ELISA, IHC-P, ICC/IF, IF.
ASGR2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ASGR2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit.