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ASGR2 / ASGPR2 抗體, 兔單抗

  • ASGR2 / ASGPR2 Antibody, Rabbit MAb, Immunohistochemistry
  • ASGR2 / ASGPR2 Antibody, Rabbit MAb, Flow Cytometry
  • ASGR2 / ASGPR2 Antibody, Rabbit MAb, Immunohistochemistry
產品資料評論相關產品實驗方法
 ASGR2 抗體產品資訊
免疫原:Recombinant Human ASGR2 / ASGPR2 protein (Catalog#13908-H07H)
Clone ID:002
Ig類型:Rabbit IgG
濃度:
內毒素:
緩衝液:0.2 μm filtered solution in PBS
抗體製備方法:This antibody was obtained from a rabbit immunized with purified, recombinant Human ASGR2 / ASGPR2 (rh ASGR2 / ASGPR2; Catalog#13908-H07H; P07307-1; Gln80-Ala311).
 ASGR2 Antibody IHC Application Image
ASGR2 / ASGPR2 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human ASGR2 in human cirrhosis with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
ASGR2 / ASGPR2 Antibody, Rabbit MAb, Immunohistochemistry
[點擊查看大圖]
Caption:
Immunochemical staining of human ASGR2 in human liver with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
 ASGR2 Antibody FC Application Image
ASGR2 / ASGPR2 Antibody, Rabbit MAb, Flow Cytometry
[點擊查看大圖]
Caption:
Flow cytometric analysis of Human ASGR2 expression on HepG2 cells. Cells were stained with purified anti-Human ASGR2, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Other ASGR2 Antibody Products

Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

Lane A: NIH3T3 Whole Cell Lysate

Lane B: Hela Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

Developed using the ECL technique.

Performed under reducing conditions.

Predicted band size:15 kDa

Observed band size:17 kDa

ASGR2 / ASGPR2 研究背景

ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit.

 ASGR2 / ASGPR2 參考資料
  • Davila S, et al. (2010) New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. 11(3):232-8.
  • Zhang X, et al. (2011) Asialoglycoprotein receptor interacts with the preS1 domain of hepatitis B virus in vivo and in vitro. Arch Virol. 156(4):637-45.
  • Guy CS, et al. (2011) Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor. Hepatology. 54(3):1043-50.
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    Size / Price
    貨號: 13908-R002-100
    目錄價: 
    單價:      (You Save: )

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”