ACE2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All ACE2 reagents are produced in house and quality controlled, including 8 ACE2 Antibody, 1 ACE2 ELISA, 52 ACE2 Gene, 7 ACE2 Lysate, 8 ACE2 Protein, 3 ACE2 qPCR. All ACE2 reagents are ready to use.

Recombinant ACE2 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc & His, C-His, C-human IgG1-Fc, C-mouse IgG1-Fc.

ACE2antibodies are validated with different applications, which are ELISA, WB, IHC-P, ELISA(Det), ELISA(Cap).

ACE2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ACE2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

ACE2ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

ACE2 Protein (8)

Species

ACE2 Protein, Rat, Recombinant (His Tag)

80031-R08H

Expression host: HEK293 Cells

Rat ACE2 / Angiotensin-Converting Enzyme 2 Protein 12345

ACE2 Protein, Human, Recombinant (Fc Tag)

10108-H02H

Expression host: HEK293 Cells

Human ACE2 / Angiotensin-Converting Enzyme 2 Protein 8398

ACE2 Protein, Human, Recombinant (His Tag)

10108-H08H

Expression host: HEK293 Cells

Human ACE2 Protein 20097

ACE2 Protein, Rhesus, Recombinant (His Tag)

90211-C08H

Expression host: HEK293 Cells

Rhesus ACE2 / Angiotensin-Converting Enzyme 2 Protein 12882

ACE2 Protein, Mouse, Recombinant (His Tag)

50249-M08H

Expression host: HEK293 Cells

Mouse ACE2 / Angiotensin-Converting Enzyme 2 Protein 11518

ACE2 Protein, Rhesus, Recombinant (Fc Tag)

90211-C02H

Expression host: HEK293 Cells

Rhesus ACE2 / Angiotensin-Converting Enzyme 2 Protein 12881

ACE2 Protein, Human, Recombinant (Fc Tag)

10108-H05H

Expression host: HEK293 Cells

Human ACE2 / Angiotensin-Converting Enzyme 2 Protein 8399

ACE2 Protein, Mouse, Recombinant (His & Fc Tag)

50249-M03H

Expression host: HEK293 Cells

Mouse ACE2 / Angiotensin-Converting Enzyme 2 Protein 11517
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ACE2 Antibody (8)

Application Clonality
Host

Anti-ACE2 Antibody

80031-R001

Specificity: Rat

Application: ELISA

Clonality: MAb

Anti-ACE2 Antibody

80031-RP02

Specificity: Rat

Application: ELISA

Clonality: PAb

Anti-ACE2 Antibody

80031-R039

Specificity: Rat

Application: IHC-P

Clonality: MAb

Rat ACE2 / Angiotensin-Converting Enzyme 2 Immunohistochemistry(IHC) 3153

Anti-ACE2 Antibody

10108-T56

Specificity: Human

Application: WB,ELISA,IHC-P

Clonality: PAb

Human CD27/TNFRSF7 Immunohistochemistry(IHC) 4765

Anti-ACE2 Antibody

80031-MM04

Specificity: Rat

Application: ELISA(Cap)

Clonality: MAb

Anti-ACE2 Antibody

80031-R003

Specificity: Rat

Application: ELISA(Det)

Clonality: MAb

Anti-ACE2 Antibody

80031-RP01

Specificity: Rat

Application: ELISA

Clonality: PAb

Anti-ACE2 Antibody

10108-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

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ACE2 ELISA KIT & match antibody elias pair set ( 1 )

ACE2 Matched ELISA Antibody Pair Set,Rat

SEK80031

Assay Range: 125 pg/ml

Rat ACE2 / Angiotensin-Converting Enzyme 2 ELISA Pair Set Standard Curve 14964

ACE2 cDNA Clone (52)

Mouse
Human
Rhesus
Rat

ACE2 qPCR Primer (3)

ACE2 Lysate (7)

Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pathological role of ACE2 in the cardiovascular, renal and respiratory systems. ACE2 also has an important role in blood pressure control. This enzyme, an homolog of ACE, hydrolyzes angiotensin (Ang) I to produce Ang-(1-9), which is subsequently converted into Ang-(1-7) by a neutral endopeptidase and ACE. ACE2 releases Ang-(1-7) more efficiently than its catalysis of Ang-(1-9) by cleavage of Pro(7)-Phe(8) bound in Ang II. Thus, the major biologically active product of ACE2 is Ang-(1-7), which is considered to be a beneficial peptide of the RAS cascade in the cardiovascular system. A physiological role for ACE2 has been implicated in hypertension, cardiac function, heart function and diabetes, and as a receptor of the severe acute respiratory syndrome coronavirus. In the acute respiratory distress syndrome (ARDS), ACE, AngII, and AT1R promote the disease pathogenesis, whereas ACE2 and the AT2R protect from ARDS. Importantly, ACE2 has been identified as a key SARS-coronavirus receptor and plays a protective role in severe acute respiratory syndrome (SARS) pathogenesis. Furthermore, the recent explosion of research into the ACE2 homolog, collectrin, has revealed a new physiological function of ACE2 as an amino acid transporter, which explains the pathogenic role of gene mutations in Hartnup disorder. This review summarizes and discusses the recently unveiled roles for ACE2 in disease pathogenesis.

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Antibody
ELISA
Gene
qPCR
Lysate
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