ABCB6: ABCB6 Protein | ABCB6 Antibody

ABCB6 Gene family

ABCB6 Protein

ABCB6 protein function

Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.

ABCB6 protein expression

Tissue specificity

Widely expressed. High expression is detected in the retinal epithelium.

Induction

Up-regulated by cellular porphyrins (at protein level). Up-regulated during erythroid differentiation (at protein level).

ABCB6 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    842.00
  • Mass (Da)
    93.00

ABCB6 Gene

ABCB6 cDNA / gene is a gene with protein product which located on 2q35. The ABCB6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, M.oryzae, N.crassa, and frog. 222 organisms have orthologs with human gene ABCB6.