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ABCA3  基因

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ABCA3 相關信號通路

ABCA3 相關蛋白、抗體、cDNA基因、ELISA試劑盒

ABCA3 相關蛋白、抗體、cDNA基因、ELISA試劑盒

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ABCA3 概述&蛋白信息

ABCA3 研究背景

結構域: Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain (By similarity).
亞細胞定位: Membrane; Multi-pass membrane protein (Potential).
組織特異性: Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
相關疾病 : Pulmonary surfactant metabolism dysfunction 3 (SMDP3) [MIM:610921]: A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid- Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似的序列: Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains.
General information above from UniProt

ABCA3 別稱

ABC3,ABC-C,SMDP3,LBM180,EST111653, [homo-sapiens]
Abc3,ABC-C,1810036E22Rik, [mus-musculus]

ABCA3 相關文獻

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