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Aminoadipate aminotransferase  基因

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RP300808 

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Aminoadipate aminotransferase 相关研究领域

Aminoadipate aminotransferase 相關信號通路

    Aminoadipate aminotransferase 概述&蛋白信息

    Aminoadipate aminotransferase 研究背景

    催化活性: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.; L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.
    輔因數: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:12126930, ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996};
    酶調控: ENZYME REGULATION: Kynurenine transaminase activity is competitively inhibited by aminoadipate, asparagine, glutamate, histidine, cysteine, lysine, 3-hydroxy-kynurenine and phenylalanine. {ECO:0000269|PubMed:18620547}.
    亞單位結構: Homodimer. {ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996, ECO:0000269|PubMed:18620547}.
    亞細胞定位: Mitochondrion {ECO:0000305}.
    組織特異性: Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
    相似的序列: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}.
    General information above from UniProt

    Aminoadipate aminotransferase 別稱

    KAT2,KATII, [homo-sapiens]
    Aadt,Kat2,KATII,mKat-2,AI875679, [mus-musculus]

    Aminoadipate aminotransferase 相關文獻

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