A4GALT cDNA Clone: Expression and Clone Vector / Plasmid

A4GALT cDNA / Gene Overview

A4GALT cDNA / gene is a protein coding gene.The A4GALT gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, fruit fly, mosquito, and frog.156 organisms have orthologs with human gene A4GALT

A4GALT cDNA / Gene Function

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.

A4GALT cDNA / Gene Sequence

LOCUS
NC_000022 29190 bp DNA linear CON 26-MAR-2018
DEFINITION
Homo sapiens chromosome 22, GRCh38.p12 Primary Assembly
ACCESSION
NC_000022 REGION: complement(42692112..42721301)
VERSION
NC_000022.11

This sequence information is just for reference only.

A4GALT Family & Reagents

Gene family

A4GALT Gene family reagents (Blood group antigens)

Approved Symbol Reagent list
ABO
ART4
BSG
CD55
CD99
GYPC
XG
Approved Symbol Reagent list
ACHE
BCAM
CD44
CD59
GYPA
ICAM4
   

A4GALT cDNA / Gene Alias

  • A14GALT
  • CD77 synthase
  • Gb3 synthase
  • Gb3S
  • globotriaosylceramide synthase
  • lactosylceramide 4-alpha-galactosyltransferase
  • P(k)

A4GALT cDNA / Gene Expression

Ubiquitous expression in kidney (RPKM 6.5), fat (RPKM 5.5) and 22 other tissues