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4-1BBL / CD137L / TNFSF9 抗體 (APC), 兔單抗

  • Carboxypeptidase B1 / CPB1 Antibody, Mouse MAb, Immunohistochemistry
  • Mouse CD137L/4-1BBL/TNFSF9 Flow Cytometry (FC) 2555
產品資料評論相關產品實驗方法
小鼠 TNFSF9 抗體產品資訊
免疫原:Recombinant Mouse 4-1BBL / CD137L / TNFSF9 protein (Catalog#50067-M07H)
Clone ID:014
Ig類型:Rabbit IgG
濃度:10 μl/Test, 0.1 mg/ml
緩衝液:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
抗體製備方法:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse 4-1BBL / CD137L / TNFSF9 (rM 4-1BBL / CD137L / TNFSF9; Catalog#50067-M07H; NP_033430.1; Arg 104-Glu 309) and conjugated with APC under optimum conditions, the unreacted APC was removed.
小鼠 TNFSF9 抗體使用指導
特異性:Mouse 4-1BBL / CD137L / TNFSF9
推薦應用:FCM
儲存方法:
小鼠 TNFSF9 Antibody FC Application Image
Carboxypeptidase B1 / CPB1 Antibody, Mouse MAb, Immunohistochemistry
[點擊查看大圖]
Caption:
4-1BBL / CD137L / TNFSF9 Antibody (APC), Rabbit MAb, Flow cytometric analysis
Other TNFSF9 Antibody Products
CD137L/4-1BBL/TNFSF9 研究背景

4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In additon, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: FCM Antibodies
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

小鼠 CD137L/4-1BBL/TNFSF9 參考資料
  • Cheung CT, (2007) Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab Invest. 87(7): 651-61.
  • Wang C, et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev. 229(1): 192-215.
  • Habib-Agahi M, et al. (2009) 4-1BBL costimulation retrieves CD28 expression in activated T cells. Cell Immunol. 256(1-2): 39-46.
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    Size / Price
    貨號: 50067-R014-A-100
    目錄價: 
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    Datasheet & Documentation

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